Oxygen therapy seems to be effective in patients with intracranial air

We sometimes use oxygen therapy to patients with pneumocephalus after craniotomy. However, I have never seen any clinical studies about this until now! I found a paper from Gore et al. In a prospective study they examined the efficacy and effect on the rate of pneumocephalus absorption. A group of patients received 100% (normobaric) supplemental 0(2) through a nonrebreather mask at 12 L/minute for 24 h and were compared to a control group. A blinded radiologist :) found a significant difference in the rate of air volume reduction in the treatment group (65%) compared to the control (31%). /Jan Reference: Normobaric oxygen therapy strategies in the treatment of postcraniotomy pneumocephalus. Gore PA, Maan H, Chang S, Pitt AM, Spetzler RF, Nakaji P. J Neurosurg. 2008 May;108(5):926-9.